Postdoctoral Fellowship in Immunotherapy

The Oncogenomics Section of the NCI Center for Cancer Research is seeking a postdoctoral fellow to join

a multidisciplinary translational research program focused on developing immune therapies for pediatric

cancers.

The fellow will generate and analyze data from Ewing sarcoma tumors using short- and long-read RNA

sequencing, immunopeptidomics, immune profiling, bioinformatics, and antigen discovery pipelines. The

project will prioritize EWSR1::FLI1/ERG, PRAME, and non-canonical epitopes in collaboration with CCR

cores and Johns Hopkins partners to develop TCR-based therapies for pediatric cancer.

Responsibilities include generating peptide-specific T cells, cloning and characterizing TCRs, defining

MHC restriction, and optimizing TCRs using single-cell sequencing, immunogenomics, spatial

transcriptomics, proteomics, and functional assays.

Candidates should be recent graduates (within 3 years) with a PhD, MD, or equivalent degree in

immunology, molecular biology, cell biology, or a related field. Hands-on experience in

immunogenomics, immunotherapy, immunology, adoptive cell therapy, gene therapy, and genome

editing is required.

If interested, please email me the following documents:

-Cover Letter

-Resume

-Contact Info of three professional references